Mannose-binding lectin deficiency is associated with early onset of polyarticular juvenile rheumatoid arthritis: a cohort study
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Mannose-binding lectin deficiency is associated with early onset of polyarticular juvenile rheumatoid arthritis: a cohort study
BACKGROUND Mannose-binding lectin (MBL) is an innate immune protein. The aim of our study was to determine whether genetically determined MBL deficiency is associated with susceptibility to juvenile rheumatoid arthritis (JRA) and whether MBL2 genotypes are associated with JRA severity. METHODS In a retrospective cohort study of 218 patients with polyarthritis (n = 67) and oligoarthritis (n = ...
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ژورنال
عنوان ژورنال: Arthritis Research & Therapy
سال: 2008
ISSN: 1478-6354
DOI: 10.1186/ar2386